https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 The DNA methylation of FOXO3 and TP53 as a blood biomarker of late-onset asthma https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42668 Wed 31 Aug 2022 16:18:23 AEST ]]> Airway Epithelial ITGB4 Deficiency Induces Airway Remodeling in a Mouse Model https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50606 Wed 28 Feb 2024 15:56:56 AEDT ]]> Integrins are double-edged swords in pulmonary infectious diseases https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52738 Wed 25 Oct 2023 08:40:27 AEDT ]]> miRNA-34b/c regulates mucus secretion in RSV-infected airway epithelial cells by targeting FGFR1 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48903 Wed 19 Apr 2023 16:32:54 AEST ]]> DNA methylation down-regulates integrin β4 expression in asthmatic airway epithelial cells https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47164 Wed 14 Dec 2022 15:49:08 AEDT ]]> Treatable Traits in Elderly Asthmatics from the Australasian Severe Asthma Network: A Prospective Cohort Study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49079 Wed 03 May 2023 16:14:55 AEST ]]> An altered sputum macrophage transcriptome contributes to the neutrophilic asthma endotype https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44806 Wed 01 May 2024 12:05:04 AEST ]]> Relationship of sputum mast cells with clinical and inflammatory characteristics of asthma https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46094 1 and FVC. Trends towards similar clinical associations with elevated MCs were observed in a paucigranulocytic subpopulation (n = 15) lacking airway eosinophilia or neutrophilia. Receiver operator characteristic (ROC) analysis showed peripheral blood eosinophil (PBE) count predicted elevated sputum eosinophils and basophils, but not MCs. Conclusions and Clinical Relevance: Sputum MCs are elevated in asthma, and their measurement may be useful as they relate to key clinical features of asthma (spirometry, asthma control, AHR). PBE count did not predict airway MC status, suggesting direct measurement of airway MCs by sensitive methods such as flow cytometry should be further developed.]]> Tue 21 May 2024 11:55:14 AEST ]]> Clinical and inflammatory features of exacerbation-prone asthma: a cross-sectional study using multidimensional assessment https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38811 Tue 08 Feb 2022 14:30:33 AEDT ]]> Clinical Subtypes of Neutrophilic Asthma: A Cluster Analysis From Australasian Severe Asthma Network https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54912 Thu 21 Mar 2024 12:03:37 AEDT ]]> Dyslipidemia Is Associated With Worse Asthma Clinical Outcomes: A Prospective Cohort Study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50719 Thu 03 Aug 2023 09:12:38 AEST ]]> The role of gut-lung axis in COPD: Pathogenesis, immune response, and prospective treatment https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:55409 Mon 27 May 2024 12:11:12 AEST ]]> Neutrophilic asthma features increased airway classical monocytes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47276 Mon 27 Mar 2023 13:58:24 AEDT ]]> Airway epithelial integrin β4 suppresses allergic inflammation by decreasing CCL17 production https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38495 Mon 09 May 2022 16:16:36 AEST ]]> Aberrant methylation of aging-related genes in asthma https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:40279 Mon 08 Aug 2022 11:55:28 AEST ]]> ITGB4 Deficiency in Airway Epithelium Aggravates RSV Infection and Increases HDM Sensitivity https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52669 Fri 20 Oct 2023 09:24:41 AEDT ]]> ITGB4 deficiency in airway epithelia enhances HDM-induced airway inflammation through hyperactivation of TLR4 signaling pathway https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52668 Fri 20 Oct 2023 09:24:13 AEDT ]]> ITGB4 deficiency induces DNA damage by downregulating HDAC1 in airway epithelial cells under stress stimulation https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52670 Fri 20 Oct 2023 09:23:42 AEDT ]]> Respiratory syncytial virus infection-induced mucus secretion by down-regulation of miR-34b/c-5p expression in airway epithelial cells https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42298 Fri 19 Aug 2022 15:05:25 AEST ]]> Sputum mast cell/basophil gene expression relates to inflammatory and clinical features of severe asthma https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49427 Fri 12 May 2023 15:16:07 AEST ]]> Dysregulation of sputum columnar epithelial cells and products in distinct asthma phenotypes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37118 Fri 03 Dec 2021 10:32:20 AEDT ]]> Involvement of epithelia-derived exosomes in chronic respiratory diseases https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49786 Fri 02 Jun 2023 17:27:41 AEST ]]>